Факультет радіофізики, біомедичної електроніки та комп’ютерних систем >
Наукові роботи. Радіофізичний факультет >

Please use this identifier to cite or link to this item: http://dspace.univer.kharkov.ua/handle/123456789/7228

Название: Interaction of new fluorescent ict-dyes with lipid membranes
Авторы: Zhytnyakovskaya, O.A.
Kutsenko, O.K.
Trusova, V.M.
Gorbenko, G.P.
Deligeorgiev, T.
Kaloyanova, S.
Lesev, N.
Ключевые слова: ICT dyes
Issue Date: 2010
Издатель: Харьковский Национальный Университет им. В.Н.Каразина
Библиографическое описание: Журнал
Серия/номер: Биофизический вестник;25(2)
Краткий осмотр (реферат): The present study was undertaken to evaluate the sensitivity of newly synthesized ICT dyes to the changes in physicochemical properties of lipid bilayer. Partitioning of ICT4 into lipid phase of the model membranes composed of zwitterionic lipid phosphatidylcholine (PC) and its mixtures with anionic lipid cardiolipin and cholesterol was followed by the decrease of fluorescence quantum yield and short- wavelength shift of emission maximum. On the contrary, ICT2 exhibited tenfold increase of the quantum yield upon interaction with liposomes, without any shift of the emission maximum. Analysis of the partition coefficients showed that inclusion of cardiolipin and choleterol into phosphatidylcholine bilayer gives rise to increase of the ICT2 incorporation into lipid phase compared to the neat phosphatidylcholine membrane.
URI: http://dspace.univer.kharkov.ua/handle/123456789/7228
Appears in Collections:Наукові роботи. Радіофізичний факультет

Files in This Item:

File Description SizeFormat
25_10.pdf521,28 kBAdobe PDFThumbnail
View Statistics

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


Valid XHTML 1.0! Яндекс цитирования DSpace Software Copyright © 2002-2010  Duraspace - Feedback