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Please use this identifier to cite or link to this item: http://dspace.univer.kharkov.ua/handle/123456789/7223

Название: Comparative analysis of molecular mechanisms of relaxation of DNA bending deformation
Авторы: Shashel, Ya.V.
Smyrnova, D.O.
Ключевые слова: DNA
molecular dynamics
protein-nucleic acids interactions
structure deformations
relaxation mechanisms
Issue Date: 2010
Издатель: Харьковский Национальный Университет им. В.Н.Каразина
Библиографическое описание: Журнал
Серия/номер: Биофизический вестник;25(2)
Краткий осмотр (реферат): Comparison of relaxation mechanisms of bending DNA deformation was performed by molecular dynamics method for two types of bending DNA from complex with 434 repressor and purine repressor. Comparative analysis of relaxation dynamics of local structure parameters characterizing DNA structure on dinucleotide level and parameters characterizing DNA structure as whole was performed. Obtained data shows that relaxation takes place in stages and each stage is characterized by similar time intervals for two bending DNA types. It is shown that character of relaxation in the initial stages of dynamics depends on the type of DNA bending deformation: for smooth curve linear changes in parameters are peculiar; for localized sharp curve changes in parameters occurs abruptly.
URI: http://dspace.univer.kharkov.ua/handle/123456789/7223
Appears in Collections:Наукові роботи. Радіофізичний факультет

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